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Page 1
Molecular pharmacology of niaprazine.
Scherman D, Hamon M, Gozlan H, Henry JP, Lesage A, Masson M, Rumigny JF. Scherman D, et al. Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(6):989-1001. doi: 10.1016/0278-5846(88)90093-0. Prog Neuropsychopharmacol Biol Psychiatry. 1988. PMID: 2853885
1. The pharmacological profile of niaprazine was investigated using in vitro ligand binding techniques. 2. Niaprazine exhibits a low affinity for the vesicular monoamine transporter and for D2, alpha 2, beta, H1 and muscarinic cholinergic receptors. ...
1. The pharmacological profile of niaprazine was investigated using in vitro ligand binding techniques. 2. Niaprazine exhibits …
Niaprazine in the treatment of autistic disorder.
Rossi PG, Posar A, Parmeggiani A, Pipitone E, D'Agata M. Rossi PG, et al. J Child Neurol. 1999 Aug;14(8):547-50. doi: 10.1177/088307389901400814. J Child Neurol. 1999. PMID: 10456769
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. ...Niaprazine was more efficacious in subjects with a mild or moderate degree of mental retardation. ...
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. ...Niaprazine was more efficacious in subjec …
Niaprazine, a selective brain catecholamine depletor.
Keane PE, Benedetti MS. Keane PE, et al. Neuropharmacology. 1979 Jul;18(7):595-600. doi: 10.1016/0028-3908(79)90110-2. Neuropharmacology. 1979. PMID: 158713 No abstract available.
The effect of niaprazine on some common sleep disorders in children. A double-blind clinical trial by means of continuous home-videorecorded sleep.
Ottaviano S, Giannotti F, Cortesi F. Ottaviano S, et al. Childs Nerv Syst. 1991 Oct;7(6):332-5. doi: 10.1007/BF00304832. Childs Nerv Syst. 1991. PMID: 1837245 Clinical Trial.
A placebo-controlled double-blind clinical trial on the effect of niaprazine on children with some common sleep disorders was carried out. ...A reliable positive effect of niaprazine on the sleep disorders considered was found. No adverse side effects were observed. …
A placebo-controlled double-blind clinical trial on the effect of niaprazine on children with some common sleep disorders was carried …
The effect of niaprazine on the turnover of 5-hydroxytryptamine in the rat brain.
Keane PE, Strolin Benedetti M, Dow J. Keane PE, et al. Neuropharmacology. 1982 Feb;21(2):163-9. doi: 10.1016/0028-3908(82)90157-5. Neuropharmacology. 1982. PMID: 6460945
Niaprazine (60 mg/kg i.p.) increased rat brain 5-hydroxyindole acetic acid (5-HIAA) concentrations 30 min after treatment, and reduced them at 3-8 hr after treatment. Rat brain 5-hydroxytryptamine (5-HT) levels were unchanged. Niaprazine also produced a short-lastin …
Niaprazine (60 mg/kg i.p.) increased rat brain 5-hydroxyindole acetic acid (5-HIAA) concentrations 30 min after treatment, and reduce …
[Syncope after niaprazine (Nopron)].
Sarda H, Benkhelifa S, Housset C, Le Loc'h H. Sarda H, et al. Arch Pediatr. 1996 Jan;3(1):90. doi: 10.1016/s0929-693x(96)80020-0. Arch Pediatr. 1996. PMID: 8745837 French. No abstract available.
[Niaprazine in behavior disorders in children. Double-blind comparison with placebo].
Franzoni E, Masoni P, Mambelli M, Marzano P, Donati C. Franzoni E, et al. Pediatr Med Chir. 1987 Mar-Apr;9(2):185-7. Pediatr Med Chir. 1987. PMID: 2958783 Clinical Trial. Italian.
The results of a randomized, double blind clinical trial are described. Niaprazine (1.5 mg/kg/day) or placebo were administered for 1 month to 20 patients (17 M-3 F; age range 6-11 years) suffering from behaviour disorders. ...No relevant side effects were observed: only i …
The results of a randomized, double blind clinical trial are described. Niaprazine (1.5 mg/kg/day) or placebo were administered for 1 …
23 results